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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CENPF
All Species:
13.03
Human Site:
S2005
Identified Species:
23.89
UniProt:
P49454
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49454
NP_057427.3
3210
367764
S2005
N
E
L
S
R
I
R
S
E
K
A
S
I
E
H
Chimpanzee
Pan troglodytes
XP_001171549
3114
357698
S1909
N
E
L
S
R
I
R
S
E
K
A
N
I
E
H
Rhesus Macaque
Macaca mulatta
XP_001105956
3113
357422
S1908
N
E
L
S
S
I
R
S
E
K
A
N
I
E
H
Dog
Lupus familis
XP_852813
1449
166096
A388
T
K
R
E
I
L
S
A
P
G
R
S
V
E
D
Cat
Felis silvestris
Mouse
Mus musculus
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510329
2965
340022
K1858
V
L
L
L
E
R
E
K
S
G
L
N
E
K
V
Chicken
Gallus gallus
O42184
1433
161009
R372
I
E
Q
L
L
A
E
R
D
L
E
R
A
E
V
Frog
Xenopus laevis
P85120
2058
236320
N997
S
L
N
Q
Q
L
Q
N
E
L
N
S
I
K
K
Zebra Danio
Brachydanio rerio
XP_002665261
2708
311087
E1647
K
I
C
K
M
E
S
E
K
T
N
G
T
D
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VJE5
1690
189046
E629
T
E
V
R
M
R
D
E
Q
I
R
E
L
N
Q
Honey Bee
Apis mellifera
XP_001120388
2064
240016
D1003
E
R
L
K
K
Q
N
D
E
L
E
S
E
N
T
Nematode Worm
Caenorhab. elegans
P02566
1966
225108
S905
S
L
F
T
N
L
E
S
T
K
T
Q
L
S
D
Sea Urchin
Strong. purpuratus
XP_796801
3636
416057
S2251
Y
Q
M
H
S
A
Q
S
E
L
E
A
V
K
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P25386
1790
206434
F729
E
P
I
N
K
I
S
F
E
E
V
E
K
L
Q
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.8
91.4
32.8
N.A.
N.A.
N.A.
N.A.
50.5
20.4
21.5
31.3
N.A.
21.3
22.9
20.1
22
Protein Similarity:
100
96.4
93.8
39.1
N.A.
N.A.
N.A.
N.A.
67.5
32.4
38.6
51.2
N.A.
35.2
41.3
36.4
43.7
P-Site Identity:
100
93.3
86.6
13.3
N.A.
N.A.
N.A.
N.A.
6.6
13.3
20
0
N.A.
6.6
20
13.3
13.3
P-Site Similarity:
100
100
93.3
40
N.A.
N.A.
N.A.
N.A.
20
20
60
13.3
N.A.
26.6
26.6
40
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
21.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
36.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
16
0
8
0
0
24
8
8
0
0
% A
% Cys:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
8
8
8
0
0
0
0
8
16
% D
% Glu:
16
39
0
8
8
8
24
16
54
8
24
16
16
39
0
% E
% Phe:
0
0
8
0
0
0
0
8
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
16
0
8
0
0
0
% G
% His:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
24
% H
% Ile:
8
8
8
0
8
31
0
0
0
8
0
0
31
0
0
% I
% Lys:
8
8
0
16
16
0
0
8
8
31
0
0
8
24
16
% K
% Leu:
0
24
39
16
8
24
0
0
0
31
8
0
16
8
0
% L
% Met:
0
0
8
0
16
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
24
0
8
8
8
0
8
8
0
0
16
24
0
16
0
% N
% Pro:
0
8
0
0
0
0
0
0
8
0
0
0
0
0
0
% P
% Gln:
0
8
8
8
8
8
16
0
8
0
0
8
0
0
16
% Q
% Arg:
0
8
8
8
16
16
24
8
0
0
16
8
0
0
0
% R
% Ser:
16
0
0
24
16
0
24
39
8
0
0
31
0
8
8
% S
% Thr:
16
0
0
8
0
0
0
0
8
8
8
0
8
0
8
% T
% Val:
8
0
8
0
0
0
0
0
0
0
8
0
16
0
16
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _